The pharmacological action and clinical application of Magnesium Sulfate when different approaehes administration

1. Take orally catharsis: 50% Magnesium Sulfate solution take orally can not been assimilated, it can form a certain osmotic pressure in the enteral, this promote the enteral keep large moisture, irritate enteric to wiggle, in order to defecating. It is often used to enteric inspection or preoperative preparation, clean the enteral toxin. Also used as some antiscolic catharsis. Usage: 50% Magnesium Sulfate solution 10ml is taken on an empty stomach in the morning, at same time to take 100-400ml water.

2. Take orally cholagogic: take high concentration (33%) Magnesium Sulfate solution, or use meatus to inject the duodenum directly, it can irritate duodenum mucosa, lead to the gallbladder contraction, make the gallbladder empty. So it can cholagogic. Usage: (33%) Magnesium Sulfate solution 10ml, three times per day, take it before meal or between meals.

3. Inject to inhibit central excitation: intramuscular 25% Magnesium Sulfate solution, 4-10ml per time; or use 25% Magnesium Sulfate solution 10ml with 5%-10% glucose injecta to mix, into 1% or 5% thick to intravenous drip.

4. Inject to extend blood vessel: usage: 10% Magnesium Sulfate solution 10ml with 5%-10% glucose injecta mix to intravenous drip, one time per day.

5. External diminish inflammation: 50% Magnesium Sulfate solution hot pack afflicted part, it can diminish inflammation, it used to treat phlebitis.